Peroxidase staining without benzidine (Foreword)

Endogenous Peroxidase Staining

The present study was set up to formulate a generally applicable schedule for the cellular demonstration of tumour index substances using routinely prepared histological material by a method which would also be reproducible and readable and allow simultaneous histological diagnosis. The carcinoembryonic antigen (Gold and Freedman, 1965) was used as the prime subject as high-quality reagents wer...

Benzidine and Dyes Metabolized to Benzidine

CARCINOGENICITY Benzidine................................................................................................3 Properties..................................................................................................................................4 Use ...................................................................................................................................

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Factors modulating benzidine carcinogenicity bioassay.

An integrated series of studies was presented in which several factors were assessed as to their capability to influence the outcome of carcinogenicity of benzidine dihydrochloride in mice. In all studies C57BL/6J X C3HeB/FeJ F1 mice of both sexes were utilized. Animals were either 6 or 1 week of age at the beginning of carcinogenic treatment. Six-week-old mice were exposed to p.o. administrati...